Anti-oxidant, Anti-inflammatory and Anti-apoptotic Effect of Adiponectin on Cerebral Ischemia Reperfusion Injury in Rats
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چکیده
منابع مشابه
Usnic acid improves memory impairment after cerebral ischemia/reperfusion injuries by anti-neuroinflammatory, anti-oxidant, and anti-apoptotic properties
Objective(s): Cerebral ischemia/reperfusion causes complex pathological mechanisms that lead to brain tissue damage. Usnic acid is a lichen secondary metabolite that has many different biological properties including anti-inflammatory and anti-oxidant activities. Therefore, the objective of the current study was to investigate the neuroprotective effects of usnic acid ...
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Objective(s): Carthamus tinctorius L. (CT) or saffloweris widely used in traditional Chinese medicine. This study investigated the effects of CT extract (CTE) on ischemia–reperfusion (I/R) brain injury and elucidated the underlying mechanism. Materials and Methods: The I/R model was conducted by occlusion of both common carotid arteries and right middle cerebral artery for 90 min followed by 24...
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Objective: Allicin, the main component which is responsible for the biological activities of garlic, exerts a broad spectrum of pharmacological activities and is regarded as a potential drug in clinical therapy. However, the mechanisms of involvement of allicin in cerebral impairment induced by global cerebral ischemia/reperfusion (I/R) remain unclear. Therefore, here, we explored the effects o...
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The present study aimed to evaluate the protective effect of gallic acid on gastric mucosal lesions caused by ischemia-reperfusion (I/R) injury in rat. Forty male rats were randomly divided into sham, control (I/R injury) and three gallic acid-pretreated groups. To induce I/R lesions, the celiac artery was clamped for 30 min and then the clamp was removed to allow reperfusion for 6 hr. Pretreat...
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ژورنال
عنوان ژورنال: American Journal of Biomedical Sciences
سال: 2019
ISSN: 1937-9080
DOI: 10.5099/aj190200090